Current GRF Funding

  • Action of Ghrelin to Prevent Chemotherapy-Induced Side Effects in Suncus murinus
  • Contribution of Disrupted Gastrointestinal Myoelectric Activity to Mechanisms of Cisplatin-Induced Acute and Delayed Nausea and Emesis
  • Novel Mechanisms Involved in Motion Sickness


​Welcome to JAR-Labs

​​Home of the Emesis Research Group

  • I am a pharmacologist interested primarily on the mechanism of action of drugs on the Brain-Gut axis
  • I have been working on mechanisms of the emetic reflex for over thirty years and have contributed to drug development for the treatment of chemotherapy-induced nausea and emesis
  • The Emesis Research Group has worked with over 30 international pharmaceutical companies on drug discovery projects
  • We apply state-of-the-art technology to advance our understanding of drug and disease mechanisms
  • We believe that collaboration and teamwork are important ingredients of successful research
  • We also work on mechanisms of diabetes, Alzheimer's and Parkinson's disease

Recent Initiatives
  • Understanding mechanisms of nausea and emesis during Covid-19
  • New models of drug- and motion-induced emesis
  • Use of correlation analyses to understand networking of physiological variables during feeding, and nausea and emesis
  • Use of a Microelectrode Array platform to establish an analytical pipeline for drugs affecting slow waves: predicting gastrointestinal side effects based on our proprietary exemplar databse

Research Impact Case broadcasted on TVB (2020)

ABI Seminar (2022)

Modern approaches to study nausea and emesis and gastric function using radiotelemetry and the microelectrode array

John A. Rudd and Julia Y.H. Liu 

Video Link

School of Biomedical Sciences

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​The School of Biomedical Sciences was formed in June, 2009 from the amalgamation of staff from the Departments of Anatomy, Biochemistry, Physiology and Pharmacology.
  • Our group belongs to the new Cancer Biology and Experimental Therapeutics Theme, with an older affiliation to the Neuro-degeneration, -development and Repair Theme.
  • We are located in a purpose-built facility on the main campus of the Chinese University of Hong Kong (CUHK).
  • In addition to an interest in drug discovery, I also teach the mechanism of action of drugs in disease to biomedical sciences, medicine and pharmacy students enrolled at CUHK.
 
  • Click here for more information.