JAR-Labs
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  • JAR-Labs
  • Emesis
    • Assessing 'Nausea'
  • GI Dysrhythmia
    • Shrew Model
    • Ferret Model
    • Mouse Model
    • Zebrafish Model
  • Alzheimer's Disease
    • Non-transgenic GI-seeded Beta-amyloid Model
  • MEA
    • Gastrointestinal
    • Acute Brain Slices
  • People
    • Dr. Z. Lu
    • Julia YH Liu
    • Jessica CM Hui
    • KHALID Aleena
    • Lingqing Yang
    • Nora, Luping LIU
    • Heidi HS Ng
    • Kate, Zitong LI
    • Sam D Cui
    • Yingyi Deng
    • M.P. Ngan
    • Former members >
      • Jiang Bin
      • Jacky Chiu Yeung, TSANG
      • Varsha Suresh
      • Charmaine JS Kung
      • Ianto B. Huang
      • Sun Yayi
      • Tu Longlong
      • Dr. R.N. Sommerville
      • H.C.E. Wang
  • Publications
  • Gut Rhythm (Start-up)

Professor John A. Rudd
陸臻賢

Room 704A
Cancer Biology and Experimental Therapeutics
School of Biomedical Sciences
Lo Kwee-Seong Integrated Biomedical Sciences Building
Chinese University of Hong Kong
Shatin
New Territories
Hong Kong SAR
Publons: https://publons.com/researcher/1859580/john-a-rudd/
ORCID: https://orcid.org/0000-0002-8316-0792

Join or visit JAR-Labs

Current GRF Funding

  • Action of Ghrelin to Prevent Chemotherapy-Induced Side Effects in Suncus murinus
  • Contribution of Disrupted Gastrointestinal Myoelectric Activity to Mechanisms of Cisplatin-Induced Acute and Delayed Nausea and Emesis
  • Novel Mechanisms Involved in Motion Sickness


​Welcome to JAR-Labs

​​Home of the Emesis Research Group

  • I am a pharmacologist interested primarily on the mechanism of action of drugs on the Brain-Gut axis
  • I have been working on mechanisms of the emetic reflex for over thirty years and have contributed to drug development for the treatment of chemotherapy-induced nausea and emesis
  • The Emesis Research Group has worked with over 25 international pharmaceutical companies on drug discovery projects
  • We apply state-of-the-art technology to advance our understanding of drug and disease mechanisms
  • We believe that collaboration and teamwork are important ingredients of successful research
  • We also work on mechanisms of diabetes, Alzheimer's and Parkinson's disease

Recent Initiatives
  • Understanding mechanisms of nausea and emesis during Covid-19
  • New models of drug- and motion-induced emesis
  • Use of correlation analyses to understand networking of physiological variables during feeding, and nausea and emesis
  • Use of a Microelectrode Array platform to establish an analytical pipeline for drugs affecting slow waves: predicting gastrointestinal side effects based on our proprietary exemplar databse
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Research Impact Case broadcasted on TVB (2020)

ABI Seminar (2022)

Modern approaches to study nausea and emesis and gastric function using radiotelemetry and the microelectrode array

John A. Rudd and Julia Y.H. Liu 

Video Link
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School of Biomedical Sciences

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​The School of Biomedical Sciences was formed in June, 2009 from the amalgamation of staff from the Departments of Anatomy, Biochemistry, Physiology and Pharmacology.
  • Our group belongs to the new Cancer Biology and Experimental Therapeutics Theme, with an older affiliation to the Neuro-degeneration, -development and Repair Theme.
  • We are located in a purpose-built facility on the main campus of the Chinese University of Hong Kong (CUHK).
  • In addition to an interest in drug discovery, I also teach the mechanism of action of drugs in disease to medicine and pharmacy students enrolled at CUHK.
  • I also have a number of administrative roles within the University including being the Director of the Laboratory Animal Services Centre, overseeing a staff of more than 60 people to provide animal-related services for the entire university and Hong Kong.
  • Click here for more information.