Current GRF Funding

  • Action of Ghrelin to Prevent Chemotherapy-Induced Side Effects in Suncus murinus
  • Contribution of Disrupted Gastrointestinal Myoelectric Activity to Mechanisms of Cisplatin-Induced Acute and Delayed Nausea and Emesis
  • Novel Mechanisms Involved in Motion Sickness


​Welcome to JAR-Labs

​​Home of the Emesis Research Group

  • I am a pharmacologist interested primarily on the mechanism of action of drugs on the Brain-Gut axis
  • I have been working on mechanisms of the emetic reflex for over thirty years and have contributed to drug development for the treatment of chemotherapy-induced nausea and emesis
  • The Emesis Research Group has worked with over 25 international pharmaceutical companies on drug discovery projects
  • We apply state-of-the-art technology to advance our understanding of drug and disease mechanisms
  • We believe that collaboration and teamwork are important ingredients of successful research
  • We also work on mechanisms of diabetes, Alzheimer's and Parkinson's disease

Recent Initiatives
  • Understanding mechanisms of nausea and emesis during Covid-19
  • New models of drug- and motion-induced emesis
  • Use of correlation analyses to understand networking of physiological variables during feeding, and nausea and emesis
  • Use of a Microelectrode Array platform to establish an analytical pipeline for drugs affecting slow waves: predicting gastrointestinal side effects based on our proprietary exemplar databse

School of Biomedical Sciences

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​The School of Biomedical Sciences was formed in June, 2009 from the amalgamation of staff from the Departments of Anatomy, Biochemistry, Physiology and Pharmacology.
  • Our group belongs to the new Cancer Biology and Experimental Therapeutics Theme, with an older affiliation to the Neuro-degeneration, -development and Repair Theme.
  • We are located in a purpose-built facility on the main campus of the Chinese University of Hong Kong (CUHK).
  • In addition to an interest in drug discovery, I also teach the mechanism of action of drugs in disease to medicine and pharmacy students enrolled at CUHK.
  • I also have a number of administrative roles within the University including being the Director of the Laboratory Animal Services Centre, overseeing a staff of more than 60 people to provide animal-related services for the entire university and Hong Kong.
  • Click here for more information.